Genetic Control · Open-Field Validation · Alpine Industrial Strategy
1992–Present
This platform documents the long-term development of a structured Ginkgo biloba cultivation and genetic selection program initiated in 1992 and operationally executed since 2021 by NORD NUC S.R.L. under the strategic research direction of TEHNOFARM S.R.L.
The project is designed as a multi-decade industrial leaf-production system based on genetic control, climatic validation and phased European deployment.
Pharmaceutical compound profiling and extract standardisation are presented separately within the GINKGO PHARMA® framework.
Historical Development Framework (1992–2016)
1992 — Botanical-pharmaceutical orientation established within TEHNOFARM S.R.L.
1995–2008 — Practical experience with externally sourced botanical raw material revealed structural limitations:
- origin inconsistency
- phytochemical variability
- absence of cultivation control
- lack of long-term plantation traceability
2009 — Strategic decision defined:
transition from third-party sourcing to controlled cultivation and proprietary genetic selection.
2011–2016 — Research framework structuring:
- continental climate feasibility analysis
- frost tolerance thresholds
- root architecture stability criteria
- plantation density modelling
- vegetative uniformity parameters
- multi-year field validation protocol
This phase established the biological and industrial architecture of the program.
Operational Phase — Republic of Moldova
Field Establishment
On 2021, a 0.3 hectare pilot plantation was established (Corbu area).
Planting scheme:
- 1.0 m between rows
- 0.5 m between plants in-row
Plant density:
≈ 20,000 plants per hectare (theoretical model)
≈ 6,000 plants within the 0.3 ha pilot area
The pilot phase serves as structural field validation under natural continental exposure.
Climatic Validation (2021–2024)
Location: Northern Republic of Moldova
Climate type: temperate continental
Climatic characteristics include:
- winter frost exposure
- seasonal snow cover
- summer heat stress
- significant annual temperature amplitude
During the 2021–2024 observation period:
- winter temperatures reached approximately −22 °C
- plants remained under open-field exposure
- no artificial winter protection was applied
Selection under these conditions confirms:
- dormancy stability
- frost tolerance
- structural resilience of root systems
- seasonal regeneration capacity
Winter stress is intentionally integrated into the selection protocol.
Current Genetic Selection Base
Parallel to the pilot plantation:
- 5,000 plants completed a two-year nursery selection cycle
- 20 visually dominant structural leaders were identified
- candidates proceed to laboratory phytochemical analysis in 2026
Selection criteria include:
- vegetative vigor
- structural symmetry
- root-to-height proportional balance
- winter survival stability
- uniform leaf mass formation
Only top-performing genotypes will proceed to clonal stabilisation.
2026–2027 — Analytical and Clonal Stabilisation Phase
2026
- laboratory evaluation of active compound profiles
- confirmation of structural-genetic leaders
- final genotype selection
2027
- initiation of In Vitro clonal multiplication
- preservation of elite genotypes
- preparation for industrial-scale deployment
This phase transitions the program from population-based selection to genetically stabilised industrial lines.
2029 — Alpine Industrial Deployment
Planned region: Piemonte (Italy)
Target surface: 4 hectares
Planting scheme:
- 2.0 m between rows
- 0.5 m between plants in-row
Estimated density:
≈ 10,000 plants per hectare
≈ 40,000 plants total (Phase I deployment)
Operational parameters:
- rain-fed cultivation (no irrigation system)
- organic-compliant regional selection
- annual canopy height control at 2 meters
- mechanical leaf harvesting system
The plantation model is dedicated exclusively to leaf biomass production.
First Industrial Harvest
Projected first industrial-scale leaf harvest: 2033
The industrial model follows a validated sequence:
Biological validation →
Genotype selection →
Clonal stabilisation →
Alpine deployment →
Mechanical harvest integration
Scaling is phased and data-driven.
Production Focus
Industrial objective:
- Ginkgo biloba leaf biomass only
The project does not include:
- ornamental production
- seed commercialisation
- nursery retail distribution
The entire architecture is designed for controlled industrial leaf production.
Institutional Architecture
Agricultural Operator — NORD NUC S.R.L.
Strategic Research Direction — TEHNOFARM S.R.L.
Corporate Structure — TF HOLDING S.R.L.
Pharmaceutical-oriented development is presented separately at:
This platform documents the biological and industrial cultivation component of the program.
Long-Term Timeline
1992 — Conceptual origin
2009 — Controlled cultivation strategy defined
2011–2016 — Research framework structuring
2021 — 0.3 ha pilot plantation established
2021–2024 — Continental climatic validation (−22 °C exposure)
2026 — Laboratory compound analysis
2027 — In Vitro clonal propagation
2029 — 4 ha Alpine deployment
2033 — First industrial harvest
The program operates on a multi-decade industrial horizon.